Barterv1 12b01-110223082825-phpapp01 (1)

Please download to get full document.

View again

All materials on our website are shared by users. If you have any questions about copyright issues, please report us to resolve them. We are always happy to assist you.
 32
 
 

Slides

  1. Plasma Lipid Transport Role of HDL Philip Barter, MBBS, FRACP, PhD Professor and Director The Heart Research Institute, Sydney, Source: International Chair on…
Related documents
Share
Transcript
  • 1. Plasma Lipid Transport Role of HDL Philip Barter, MBBS, FRACP, PhD Professor and Director The Heart Research Institute, Sydney, Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org Australia
  • 2. PPllaassmmaa LLiippiidd TTrraannssppoorrtt Liver FFCC CCEE TTGG CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids TG: triglycerides CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids TG: triglycerides FFA Adipose tissue Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org
  • 3. PPllaassmmaa LLiippiidd TTrraannssppoorrtt Liver VLDL FFCC CCEE CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG Adipose tissue CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids TG: triglycerides FFA CCEE
  • 4. PPllaassmmaa LLiippiidd TTrraannssppoorrtt CCEE Liver CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LPL: lipoprotein lipase TG: triglycerides FFA Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org LLPPLL FFA FFCC TTGG TTGG CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LPL: lipoprotein lipase TG: triglycerides VLDL Adipose and other tissues Adipose tissue CCEE
  • 5. FFCC CCEE CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG PPllaassmmaa LLiippiidd TTrraannssppoorrtt CCEE Liver LDL TTGG VLDL TTGG LLPPLL FFA Adipose tissue CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LPL: lipoprotein lipase TG: triglycerides Adipose and other tissues FFA CCEE
  • 6. FFCC CCEE CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG PPllaassmmaa LLiippiidd TTrraannssppoorrtt CCEE LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr Liver LDL Liver Cell in peripheral tissue TTGG TTGG TTGG VLDL LLPPLL FFA Adipose tissue CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LPL: lipoprotein lipase TG: triglycerides Adipose and other tissues FFA CCEE CCEE
  • 7. FFCC CCEE CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG New synthesis PPllaassmmaa LLiippiidd TTrraannssppoorrtt FFCC LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr Liver LDL Liver Cell in peripheral tissue TTGG TTGG TTGG VLDL LLPPLL FFA Adipose tissue CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LPL: lipoprotein lipase TG: triglycerides Adipose and other tissues FFA CCEE CCEE CCEE
  • 8. FFCC CCEE CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis PPllaassmmaa LLiippiidd TTrraannssppoorrtt LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr TTGG CCEE Liver HDL LDL Liver Cell in peripheral tissue TTGG TTGG CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides TTGG VLDL LLPPLL FFA LLCCAATT Adipose tissue Adipose and other tissues FFA CCEE CCEE CCEE FFCC
  • 9. FFCC CCEE CCEE CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis PPllaassmmaa LLiippiidd TTrraannssppoorrtt LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr Liver LDL Liver Cell in peripheral tissue TTGG TTGG TTGG TTGG VLDL LLPPLL FFA Adipose tissue LLCCAATT CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Adipose and other tissues HDL FFA CCEE CCEE CCEE CCEE FFCC
  • 10. FFCC CCEE CCEE CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis PPllaassmmaa LLiippiidd TTrraannssppoorrtt LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr Liver LDL Liver Cell in peripheral tissue TTGG TTGG TTGG TTGG VLDL LLPPLL FFA Adipose tissue LLCCAATT CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Adipose and other tissues HDL FFA CCEE CCEE CCEE CCEE FFCC
  • 11. PPllaassmmaa LLiippiidd TTrraannssppoorrtt FFCC CCEE CCEE CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis Bile LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr Liver LDL Liver Cell in peripheral tissue TTGG TTGG TTGG TTGG VLDL LLPPLL FFA Adipose tissue FFCC LLCCAATT CE: cholesteryl ester FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Adipose and other tissues HDL FFA CCEE CCEE CCEE CCEE FFCC
  • 12. FFCC CCEE CCEE FFCC CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis PPllaassmmaa LLiippiidd TTrraannssppoorrtt LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr Liver LDL Liver Cell in peripheral tissue Adipose tissue TTGG TTGG TTGG TTGG VLDL LLPPLL FFA LLCCAATT Adipose and other tissues HDL FFA CCEETTPP Bile CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides CCEE CCEE CCEE CCEE FFCC
  • 13. Dyslipidemia in Diabetes and the MMeettaabboolliicc SSyynnddrroommee FFCC CCEE CCEE FFCC CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis CCEE FFCC LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr CCEE Liver LDL Liver Cell in peripheral tissue Adipose tissue TTGG TTGG TTGG TTGG VLDL LLPPLL FFA LLCCAATT Adipose and other tissues HDL FFA CCEETTPP Bile CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides CCEE CCEE
  • 14. Dyslipidemia in Diabetes and the MMeettaabboolliicc SSyynnddrroommee FFCC CCEE CCEE FFCC CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis CCEE FFCC LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr CCEE Liver LDL Liver Cell in peripheral tissue Adipose tissue TTGG TTGG TTGG TTGG VLDL LLPPLL FFA LLCCAATT Adipose and other tissues HDL ­ FFA CCEETTPP Bile CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides CCEE CCEE
  • 15. Dyslipidemia in Diabetes and the MMeettaabboolliicc SSyynnddrroommee FFCC CCEE CCEE FFCC CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis CCEE FFCC LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr CCEE Liver LDL Liver Cell in peripheral tissue Adipose tissue TTGG TTGG TTGG TTGG ­ VLDL LLPPLL FFA LLCCAATT Adipose and other tissues HDL ­ FFA CCEETTPP Bile CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides CCEE CCEE
  • 16. Dyslipidemia in Diabetes and the MMeettaabboolliicc SSyynnddrroommee FFCC CCEE CCEE FFCC CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis CCEE FFCC LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr CCEE Liver LDL Liver Cell in peripheral tissue Adipose tissue TTGG TTGG TTGG TTGG FFA LLCCAATT Adipose and other tissues ¯ LLPPLL HDL ­ FFA ­ VLDL CCEETTPP Bile CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides CCEE CCEE
  • 17. Dyslipidemia in Diabetes and the MMeettaabboolliicc SSyynnddrroommee FFCC CCEE CCEE FFCC CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG TTGG New synthesis CCEE FFCC LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr CCEE Liver LDL Liver Cell in peripheral tissue Adipose tissue TTGG TTGG TTGG TTGG FFA Adipose and other tissues ¯ LLCCAATT ¯ HDL ­ FFA ­ VLDL ¯ LLPPLL CCEETTPP Bile CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides CCEE CCEE
  • 18. Dyslipidemia in Diabetes and the MMeettaabboolliicc SSyynnddrroommee FFCC CCEE CCEE FFCC CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org TTGG CCEETTPP TTGG New synthesis CCEE FFCC LLDDLL rreecceeppttoorr LLDDLL rreecceeppttoorr CCEE Liver LDL Liver Cell in peripheral tissue Adipose tissue TTGG TTGG TTGG TTGG FFA Adipose and other tissues ­ FFA ­ VLDL ¯ LLPPLL ¯ LLCCAATT ¯ HDL Bile CE: cholesteryl ester CETP: cholesteryl ester transfer protein FC: free cholesterol FFA: free fatty acids LCAT: lecithin cholesterol acytransferase LPL: lipoprotein lipase TG: triglycerides CCEE CCEE
  • 19.  www.cardiometabolic-risk.org Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org
  • Related Search
    We Need Your Support
    Thank you for visiting our website and your interest in our free products and services. We are nonprofit website to share and download documents. To the running of this website, we need your help to support us.

    Thanks to everyone for your continued support.

    No, Thanks